Shine a light on the future of AATD treatment

Discover the AATD clinical research study

The AATD clinical research study is exploring an investigational treatment to find out how safe it is and how well it works for people living with alpha-1 antitrypsin deficiency (AATD) who have the PiZZ genotype.

This website will tell you more about the AATD clinical research study, including what it involves and who can take part. If you are interested in taking part, you can see if you qualify by clicking on the ‘Can I take part?’ tab at the top of this page or by clicking on the button below.

Privacy notice

By answering the following pre-screening questions, you agree to provide your information to We Are COUCH Ltd (“COUCH Health”, “we” or “us”), a service provider of the sponsor of this study, Vertex Pharmaceuticals Incorporated (Vertex). The categories of information collected via this questionnaire include: your name and contact information, information about your health and lifestyle, and any other information that you provide. Your information will be used only to determine whether you are eligible for this research study and, if you consent, to inform you of potential Vertex research studies in the future. It will not be shared with Vertex in any way that could identify you. You will also have the option to delete the information after you complete the pre-screening process.

If your answers to the questionnaire indicate you may be eligible for the study and you elect to share your contact information, COUCH Health will share your information with Circuit Clinical, who is also a service provider to Vertex on this study, and who will contact you to do a full pre-screening. Based on the results of that screening, and with your permission, your information would be shared with a research site. We will not share your personal information with anyone outside of this study other than as required by law, and we will not sell personal information collected from you as part of this study screening.

If you are not found to be eligible for this study, you will have the option for COUCH Health to keep your information on file for a period of time that you elect so that you can be contacted if the eligibility criteria change for the AATD study and/or for future Vertex studies.

For a fuller description of Vertex’s privacy practices, and of your privacy rights if you are a California resident, please see Vertex’s privacy policy.

If you have a question or want to exercise your privacy rights detailed in the above privacy policy, please contact COUCH at as Vertex will not receive your identifiable information.